Radiographic Evidence of Diffuse Large B-cell Lymphoma Presenting as Carpal Tunnel Syndrome

Any space-occupying lesion in the carpal tunnel can present with median nerve compression and the symptomatology of carpal tunnel syndrome (CTS). Typically, history and physical examination reveal sufficient findings to warrant further investigation with electrophysiologic testing; imaging studies, however, are not routinely considered. Here, we present a case of CTS resulting from carpal tunnel infiltration by a soft-tissue, non-Hodgkin lymphoma as evidenced by non-contrast MRI (magnetic resonance imaging).